【Detection principle】 This product uses fluorescence immunochromatography to quantitatively detect the Ddimer content in serum/plasma. Basic principle: The nitrocellulose membrane is marked with T and C lines, and the T line is coated with antibody A that specifically recognizes D-dimer. The binding pad is sprayed with another fluorescent nanomaterial-labeled antibody B that can specifically recognize D-dimer, and the D-dimer in the sample first binds to the nanomaterial-labeled antibody B to form a complex, and then upward chromatography, the complex binds to the T-line antibody A to form a sandwich structure, and when the excitation light is irradiated, the nanomaterial emits a fluorescent signal, and the strength of the signal is positively correlated with the concentration of Ddimer in the sample.
【Detection Purpose】 D-dimer is the simplest fibrin degradation product, and elevated D-dimer levels indicate hypercoagulability and secondary hyperfibrinolysis in vivo. Therefore, D-dimer concentration is of great significance for the diagnosis, efficacy evaluation and prognosis of thrombotic diseases.
